Changing Trends in Epidemiology of Candidiasis and Role of Non-Albicans Candida Species

In recent years, the increased incidence of mycosis in general and candidiasis in particular is reported in various studies.

Among various mycotic infections, candidiasis has greatest effect due to its frequency and the severity of its complications.

Candida spp. can elicit infections in immunocompetent as well as immunocompromised individuals but the incidence of candidiasis is more in immunocompromised hosts. Therefore candidiasis can be rightly called as “disease of diseased”.

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Interaction of Helicobacter Pylori with Other Microbiota Species in the Development of Gastric Cancer

Gastric adenocarcinoma is the second-leading cause of cancer-related death in the world. Helicobacter pylori is a Gram-negative bacterial species that selectively colonizes gastric epithelium.

The resulting chronic infection is the most significant risk factor for gastric adenocarcinoma identified so far.

In the host, H. pylori interacts with microorganisms, which is likely involved in the development of gastric cancer. To identify H. pylori-associated bacteria and explore the contributions of these inter-bacterial events in the process of gastric cancer, we examined the interactions of H.

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Recent Trends in Pharmaceutical Biotechnology

The foundations of pharmaceutical biotechnology mainly lie in the capability of plants, microorganism and animals to produce low and high molecular weight compounds useful as therapeutics.

Although molecules from plants and microorganisms are preferred extraction from plant biomass needs tedious downstream processing while in case of microorganisms it is easy with fewer amounts of impurities.

Pharmaceutical biotechnology is poised to flourish for the last 4-6 decades with the advent of recombinant DNA technology and metabolic engineering supported by the well-developed bioprocess technology. Large scale production and cost effectiveness and affordability could be achieved by way of synergising all these technologies.

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